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Автор: Umesh V. Banakar
Название: Pharmaceutical Dissolution Testing
Издательство: CRC Press
Год: 1991
ISBN: 9780824785673; 0824785673
Серия: Drugs and the Pharmaceutical Sciences (Book 49)
Язык: English
Формат: pdf
Размер: 30,3 mb
Страниц: 456
The importance of dissolution rate on clinical performance of drugs and drug delivery systems has long been recognized. It is the overwhelmingly important property of dosage forms that contributes to the rate and extent of drug availability to the body and, as such, is deserving of the effort that has been put forth to develop dissolution systems that provide fundamental information on the dissolution process of many drugs and chemicals as well as meaningful in vitro dissolution system models that can be correlated with some index of in vivo performance.
Since dissolution is extremely important in pharmaceutical systems, particularly solid dosage forms, each chapter of this book is devoted to a specific area in dissolution technology. Each area is discussed in sufficient depth with regard to historical background and development, theoretical and practical aspects, and current status. A wide variety of examples, citing references, along with rational guidelines for potential applications in practice are provided.
It is the intention of this book to present a consolidated update of and comprehensive information on dissolution technology that is not otherwise currently available as a single source, and to promote better understanding and fuller appreciation of the phenomenon.
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