Название: Base Editors: Methods and Protocols
Автор: Bae Sangsu, Song Beomjong
Издательство:Humana Press
Год: 2023
Формат:PDF
Страниц: 237
Размер: 11,4 МБ
Язык: English

This volume explores base editors (BEs), an invaluable CRISPR-based genome editing tool with a wide variety of versatile applications. Beginning with an overview of BEs, their diverse variants, and computational tools, the book continues with experimental applications of BEs for disease modeling in mammalian cells and generating mutagenic mice, therapeutic base editing strategies, which covers delivery methods of BE-encoded DNA plasmids, mRNAs, or ribonucleoproteins through viruses or non-viral lipid nanoparticles, and lastly, the use of BEs in plants and bacteria. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Название: The Basics of Molecular Biology
Автор: Alexander Vologodskii
Издательство:Springer
Год:2023
Формат:PDF
Страниц:198
Размер: 37,4 МБ
Язык: English

Accessible and comprehensive, this book describes the universal cellular nature of living organisms and is an indispensable tool for anyone in the sciences who wishes to get a quick overview of molecular biology. Individual chapters cover nucleic acids and proteins, genetic code and protein synthesis, the fidelity of transferring genetic information to the next generations, and the regulation of various processes inside the cells. Special attention is paid to new areas rising from modern DNA sequencing technologies which transform biology.

Название: Genomic Data Sharing: Case Studies, Challenges, and Opportunities for Precision Medicine
Автор: Mccormick J.B., Pathak J.
Издательство: Academic Press
Год: 2023
Формат:PDF
Страниц: 232
Размер: 13,5 МБ
Язык: English

Genomic Data Sharing: Case Studies, Challenges, and Opportunities for Precision Medicine provides a comprehensive overview of current and emerging issues in genomic data sharing.

Название: Основы физики атомного ядра: Ядерные технологии
Автор: Барсуков О.А.
Издательство: М.: ФИЗМАТЛИТ
Год: 2011
Cтраниц: 560
Формат: pdf
Размер: 16 мб
Язык: русский

Обобщена информация о фундаментальных проблемах физики атомного ядра. Теория процессов на ядерном уровне излагается в сочетании с данными наблюдений, в значительной мере получаемых с помощью ядерных спектроскопических методов. Рассматриваются технологии, применяемые в ядерной энергетике и экспериментальной физике микрочастиц.

Название: Ribosome Biogenesis: Methods and Protocols
Автор: Entian Karl-Dieter
Издательство: Humana
Год:2022
Формат:PDF
Страниц: 527
Размер: 10,3 МБ
Язык: English

This Open Access volume provides comprehensive reviews and describes the latest techniques to study eukaryotic ribosome biogenesis. For more than 50 years ribosomes are a major research topic. Our knowledge about ribosome biogenesis and function such as transcription, mRNA modification, and translation was the sine qua non for developing the powerful RNA-based vaccines against RNA-viruses causing the world-threatening Covid-19 pandemia.

Название: Earth: Portrait of a Planet, 7th edition
Автор: Stephen Marshak
Издательство: W. W. Norton & Company
Год: 2022
Формат: EPUB
Размер: 229 Мб
Язык: английский / English

The gold standard text for helping students visualize and understand geologic processes makes hands-on and real-world exploration easier and more impactful than ever, in any course setting. New 3D specimen and digital elevation models, with corresponding Smartwork exercises, allow students to examine specimens and sites as if they were in the field or lab. And new highly visual “Practice What You Know” and “What Can You See?” activities at the end of each chapter and in Smartwork help students synthesize and apply important concepts like a geologist. Thoroughly updated with current events and essential data, the Seventh Edition also reveals the dynamism of geology and how it impacts our lives.

Название: Secrets of the Seas: A Journey into the Heart of the Oceans
Автор: Alex Mustard, Callum Roberts
Издательство: Bloomsbury
Год: 2016
Формат: EPUB
Размер: 139 Мб
Язык: английский / English

A superb photographic celebration of marine life. Our seas are host to an extraordinary variety of plant and animal life, but much of it remains mysterious and great imagery is surprisingly hard to find. Alex Mustard is one of the world’s leading underwater photographers and his images are so crisp and immediate that the animals seem to swim out of the water towards you. This beautiful book gathers together a selection of his award-winning images and a number of new ones to create a vivid picture of the seas and oceans and the animals that inhabit them, each chapter accompanied by a 1500 word essay and extended captions written by leading natural history writer, Professor Callum Roberts.

Название: 21st Century Astronomy, 7th Edition
Автор: George Blumenthal, Stacy Palen
Издательство: W. W. Norton & Company
Год: 2022
Формат: EPUB
Размер: 335 Мб
Язык: английский / English

Fostering scientific literacy, engaging every student. Comprehensive and authoritative, 21st Century Astronomy fosters scientific literacy by offering carefully crafted activities that help students apply the process of science to astronomy, the news, and the world. The 21st Century learning package provides the most up-to-date astronomy research, engaging students as they prepare for lecture, perform in-class activities, and complete meaningful homework assignments―both in person and online. Lead author Stacy Palen draws on her experience teaching at an open enrollment university to build intentionality and transparency into every aspect of the learning package, giving activities a clear purpose and making them easy to execute without special equipment. Norton’s service supports every instructor, every step of the way.

Название: Гляциологический словарь
Автор: Котляков В.М. (ред.)
Издательство: Л.: Гидрометеоиздат
Год: 1984
Cтраниц: 528 с. + XXXII с. ч/б фотографий- иллюстраций
Формат: pdf
Размер: 40 мб
Язык: русский

Книга представляет собой первый в мире толковый словарь по гляциологии. Содержит около 2200 терминов, охватывающих все виды снега и льда: ледники, снежный покров, лавины и гляциальные сели, морские, речные и озерные льды, подземные льды и наледи. Термины не только определяются, но и раскрываются, поясняется суть связанных с ними процессов и явлений. Словарь иллюстрирован рисунками и фото и снабжен справочными материалами.

Название: Statistical Population Genomics
Автор:Dutheil J.Y.
Издательство:Springer
Год: 2021
Формат:PDF
Страниц:467
Размер: 29,9 МБ
Язык: English

With the advent of so-called “next generation” sequencing technologies, the study of genetic variation in populations gained a new dimension, turning population genetics into population genomics. While a scaling-up in data set size accompanied this shift, population genomics is more than just “big data” population genetics: because the objects of study here are “genomes” and not only “multiple genes,” the newly emerging field of population genomics comes along with its specific biological questions and statistical models.